Van de Ven Brace Ends The Toffees' Run at Brand New Stadium
Micky van de Ven emerged as the initial defender to net two goals in a Premier League game for Spurs since the Belgian defender in spring 2013.
Match summary
The Spurs defender nods into the net twice in first half
The home side's Jake O'Brien has equalizer disallowed after VAR review
Pape Matar Sarr scores third in 89th minute
The defeat is the Merseyside club's first at their new ground
The Tottenham defender scored on two occasions as Tottenham extended their unbeaten run in away games in the top division and delivered Everton their initial loss at Hill Dickinson Stadium.
Everton were unbeaten in their last five matches at their new ground at the dockside location, having left their historic home behind after more than a century at the end of the previous campaign.
But Tottenham's leader Van de Ven struck twice from set-pieces in the first half to place their strong form at jeopardy, and they were failed to mount a comeback before the midfielder - set up by former Toffees attacker the Brazilian - headed home a final goal to seal the victory.
Jake O'Brien thought he had equalized the tally five minutes after the defender's first goal, glancing a powerful header past the Spurs keeper from an set-piece.
Beto, in the meantime, missed a number of chances, while Vicario made a succession of fine stops to guarantee the London club went five matches on the road unbeaten in the Premier League.
But the VAR intervened, instructing Craig Pawson to review the score on the screen and the referee decided that the winger and Iliman Ndiaye were in offside positions and had impeded with the Spurs keeper.
The win moves the manager's team into third place in the division, five points off local foes and table-toppers Arsenal.
The Merseyside club stay in 14th position and are half a dozen points clear of the relegation zone.
Tottenham analysis: Van de Ven excels in duties at each end of pitch
After a uninspiring weekday display in the Champions League against the French side, where they mustered a mere two shots on goal, the manager opted for the French striker up front instead of former Toffees player the Brazilian.
The summer signing was failed to influence the game before being replaced for the substitute after an hour on the pitch, but it emerged he proved unnecessary in the end.
Centre-back the Dutchman transformed into an attacking force to be reckoned with.
Spurs' opening strike came from a cleverly executed corner routine, with Rodrigo Bentancur heading the ball back across the face of goal for an free the defender to score.
And the captain - filling in as captain in the Argentine's unavailability - notched his next goal in added time as he rose above the England keeper to head home.
The Dutchman was equally impressive in defensive duties, partnering well with his defensive colleague as the pair dealt excellently with the 34 crosses thrown their way by the opposition.
Toffees breakdown: Everton missing striker's instinct
The club's recent stadium had been a fortress, but it seems the novelty may have faded slightly and supporters headed to the gates after Sarr's final goal for Tottenham.
The end in the team's winning streak at home will not be a major concern for David Moyes, but their striker situation are.
The forward and the other striker - the Toffees' pair of recognised strikers - had netted only a single goal between them before the weekend's match.
And they were unable to add to that poor tally on a wet and gloomy night on Merseyside.
Beto's form was summed up when he chose to bicycle-kick a clear chance from near the goal, despite having space and time to readjust for a more conventional attempt that would have challenged Vicario.
Barry, too, was unable to influence the game after replacing the starter in the 65th minute.
It was not for a shortage of opportunity. The majority of Everton's attacks came through the winger and the forward, who tirelessly whipped dangerous balls into the Tottenham penalty area.
Upcoming fixtures for these two sides?
The Toffees: The team head to Sunderland in the Premier League on Monday, 3 November at 20:00 GMT.
Tottenham: The London club travel to Newcastle's ground on late October for their next round League Cup match against the Magpies.